News

Dr. Ángel Raya’s group receives funding from La Marató 3Cat dedicated to cardiovascular diseases

Stem Cell Potency group, lead by Dr. Ángel Raya at the P-CMR[C] and IDIBELL, together with three other research teams from IDIBELL, have been awarded by La Marató 3Cat Foundation.

1st RegenBell symposium on Stem Cells and Regenerative Medicine

We are pleased to announce the First RegenBell symposium on Stem Cells and Regenerative Medicine, which will take place on November 27-28th at the Institut d’Estudis Catalans, downtown in Barcelona. The primary goal of the symposium is to establish an inclusive and collaborative platform for scientists interested in Regenerative Medicine.

Researchers outline the mechanisms that control the conversion between fetal and adult intestinal stem cells

Deciphering the functioning of some transcription factors in the formation of the intestine has been the objective of the team led by Professor Kim Bak Jensen, from the Novo Nordisk Foundation of Stem Cell Medicine (reNEW), in which Dr. Jordi Guiu has also participated.

A heart stem cell-based model reveals why the same mutation affects two siblings with heart disease differently

Thanks to the model, the IDIBELL team detected that one of the siblings had an additional genetic variant responsible for the greater severity of the pathology. These models offer the possibility of exploring each patient’s pathology and designing an individualized approach.

New study identifies an epigenetic signature associated to the rare genetic disorder GATA2 deficiency

The results show that patients with this disorder have abnormal genetic and epigenetic patterns, which could contribute to the development of diverse clinical manifestations, such as compromise the ability of blood cell production.

M Carolina Florian new ICREA Research Professor

Dra. M Carolina Florian, group leader at IDIBELL, has been appointed as an ICREA Research Professor. ICREA, the Catalan Institution for Research and Advanced Studies, offers permanent, tenured positions to the most talented and extraordinary scientists and academics to come and work in Catalonia. Over the years these positions have become a synonym for global academic excellence.

The first meeting of the Working Groups of the project GENERATION OF HUMAN INDUCED PLURIPOTENT STEM CELLS FROM HAPLO-SELECTED CORD BLOOD SAMPLES (HAPLO-IPS)

The project aims to create a collaborative network for induced pluripotency stem cells (iPS) homozygous for the most frequent HLA haplotypes generation.

A drug that boosts the regeneration of stem cells extends life expectancy in mice

The work focuses on endogenous blood stem cell rejuvenation as a possible strategy to regenerate tissues and improve the health and life expectancy of the elderly.

It starts a project to create a collaborative network for the generation of stem cells compatible with a high percentage of the population

The project aims to create a collaborative network for induced pluripotency stem cells (iPS) homozygous for the most frequent HLA haplotypes generation.

A study describes a new way to generate insulin-producing cells

Researchers from the Karolinska Institute in Sweden, in collaboration with Meritxell Rovira from IDIBELL, the P-CMRC, and the UB show that a recently identified molecule stimulates the formation of new insulin-producing cells in zebrafish and in mammalian tissues.

New mural in tribute to Dr. Anna Veiga

The mural is located in the CEIP Pinedo of Valencia and is a piece by the artist Marta Lapeña. This is the mural number 27 of the project with which the UPV and Las Naves are filling the Valencian educational centers with science and art, in feminine.

Begins the exchange program between IDIBELL and SZBL

It begins the selection of candidates to carry out a doctoral program in Regenerative Medicine between the SZBL and the IDIBELL. The program will run mainly at SZBL and will have a minimum six months stay at IDIBELL.

Joint SZBL-IDIBELL PhD Exchange Program (2022 Call)

SZBL and IDIBELL launch their joint PhD Exchange Program call for 2022, with the aim of fostering collaboration in research between both institutions in the field of Regenerative Medicine and providing exceptional training in the field for graduated students by promoting mobility and allowing interaction with outstanding researchers.

The generation of a stem cell-derived neurofibroma model opens the door to new treatments development

Neurofibromas are tumors of the peripheral nervous system, which develop in people with a hereditary disease, and they are the main cause of death among those people.

Nanopolymer treatment prevents the formation of protein aggregates in neurons derived from Parkinson’s patients

One of the hallmarks of Parkinson’s disease is the abnormal accumulation of the α-synuclein protein that causes neuronal death responsible for motor impairments. Dendrimers are highly branched polymers that decrease α-synuclein accumulation in dopaminergic neurons derived from patient stem cells.

Pancreatic beta-cell boost in mice paves way for future diabetes treatments

A research team from IDIBELL, CRG and UB has uncovered the role of a gene that is critical to boosting the number of insulin-producing cells during the early development of the pancreas. The findings could bolster diabetes research efforts and eventually lead to new replacement therapies for the disease.

Identified an early neuronal dysfunction in Parkinson’s that could help early diagnosis

Researchers from IDIBELL and the University of Barcelona (UB) have described that neurons derived from Parkinson’s patients show impairments in their transmission before neurodegeneration.

CRISPR/Cas9 Human Embryo Genome Editing for the Study of Genes Related to Early Embryo Development

Dr. Anna Veiga is leading the project CRISPR/Cas9 human embryo genome editing (GE) for the study of genes related to early embryo development.

P-CMR[C] researchers define a new mechanism of aging in a bone marrow stem cell in women

To equilibrate the gene expression between XX females and XY males, one of female X chromosomes is inactivated. Researchers from IDIBELL Regenerative Program has discovered that this inactivation is affected in bone marrow aged stem cells.

The group led by Dr. Alessandra Giorgetti receives a grant from the GESMD to study myelodysplastic syndrome

The research group led by Dr. Alessandra Giorgetti, leader of the research group “Biology of Hematopoietic Stem Cells and Leukemogenesis” of IDIBELL, and professor at the UB, has received a grant of € 15,000 from the GESMD (Spanish Group of Myelodysplastic Syndromes), a group of which Giorgetti is an active member.

The team led by Dr. M. Carolina Florian receives a European grant of 2 million euros to study bone marrow rejuvenation

With this project, Dr. M Carolina Florian, aims to improve the survival and quality of life of elderly patients undergoing chemotherapy. The project will study the regeneration of bone marrow tissues after cancer therapy and will seek new strategies to enhance it.

The P-CMR[C] organize an open session to present the results of the EoI Call for Collaborative Projects

We are organizing a scientific session with all the awarded projects, where all participant groups will present the research performed and the collaborations born thanks to these projects.

Jordi Guiu, the new group leader of the Regenerative Medicine Program

Jordi Guiu joins to P-CMR[C] as group leader and opens the Cell Plasticity and Regeneration group

Artificial intelligence, a new tool against leukemia

Dr. M. Carolina Florian (Program of Regenerative Medicine, IDIBELL, Spain) and Prof. Medhanie Mulaw (Ulm University, Germany) will receive more than 800.000 euros from the “La Caixa” Foundation to apply deep learning to investigate leukemia in the elderly