Our Lines – P-CMRC

Available lines

Available hiPSC lines

nº	Name	Gender	Age	Cell Type	Reprogram. Method	Type	Disease	Mutation
nº	Name	Gender	Age	Cell Type	Reprogram. Method	Type	Disease	Mutation
1	KiPS3F-7	M	?	keratinocytes	integrative	retrovirus	control
2	KiPS4F-1	M	?	keratinocytes	integrative	retrovirus	control
3	KiPS4F-8	M	?	keratinocytes	integrative	retrovirus	control
4	cFA404-KiPS4F-1	M	?	keratinocytes	integrative	retrovirus	corrected Fanconi anemia
5	cFA404-KiPS4F-3	M	?	keratinocytes	integrative	retrovirus	corrected Fanconi anemia
6	XF-iPSF44-3F-1	M	3	fibroblasts	integrative	retrovirus	control
7	XF-iPSF44-3F-2	M	3	fibroblasts	integrative	retrovirus	control
8	[GA]FiPS4F	F	?	fibroblasts	integrative	retrovirus	Glutaril aciduria dehidrog. defic.
9	HKiPS4F	F	30	hair keratinocytes	integrative	retrovirus	control
10	CBiPS6-2F-4	M	0	CD133+ cord blood	integrative	retrovirus	control
11	CBiPS30-4F-3	M	0	CD133+ cord blood	integrative	retrovirus	control
12	CBiPS30-4F-5	M	0	CD133+ cord blood	integrative	retrovirus	control
13	CBiPS32-2F-2	F	0	CD133+ cord blood	integrative	retrovirus	control
14	FiPS-3F-1	M	3	fibroblasts	integrative	retrovirus	control
15	CBiPS32-3F-10	F	0	CD133+ cord blood	integrative	retrovirus	control
16	CBiPS32-3F-12	F	0	CD133+ cord blood	integrative	retrovirus	control
17	[CRTRd]FiPS3067-4F-9	M	adult	fibroblasts	integrative	retrovirus	Creatine Deficiency Syndrome	gene CRTR, c.1631 C>T
18	[CRTRd]FiPS3819-4F-2	M	adult	fibroblasts	integrative	retrovirus	Creatine Deficiency Syndrome	gene CRTR, c.1396 G>A
19	[AD]FiPSAG07645-4F-17	F	adult	fibroblasts	integrative	retrovirus	Alzheimer disease	gene PSEN1, A246E
20	[PD] FiPS022-V4F-15	M	?	fibroblasts	integrative	retrovirus	Parkinson disease	gene LRKK2 G2019S heterozygote with early onset PD (40)
21	[GD]FiPS-4F-21c	F	?	fibroblasts	integrative	lentivirus	Gaucher disease	gene GBA1, 721 G→A, 1448 T→C
22	[TSD] FiPS-4F-3-1	M	?	fibroblasts	integrative	retrovirus	Tay-Sachs disease	gene HEXA, heterozygote mutation c.1260G> C, c.1330 +1 G> A
23	FiPS-4F-7	M	3	fibroblasts	integrative	retrovirus	control
24	FiPS-4F-8	M	3	fibroblasts	integrative	retrovirus	control
25	[ctrl.PD]FiPS005-4F-9	F	56	fibroblasts	integrative	retrovirus	control (sister Parkinson disease)	control of [PD]FiPS006-4F-11
26	[PD]FiPS031-4F-1	M	48	fibroblasts	integrative	retrovirus	Parkinson disease	gene SNCA, A53T
27	[PD]FiPS006-4F-11	F	53	fibroblasts	integrative	retrovirus	Parkinson disease	gene PINK1, Q456Xhom
28	CBiPS 2F-1c	F	0	CD133+ cord blood	integrative	retrovirus	control
29	CBiPS 4F-10	F	0	CD133+ cord blood	integrative	retrovirus	control
30	CBiPS 4F-3a	F	0	CD133+ cord blood	integrative	retrovirus	control
31	FiPS Ctrl1-Ep6F-5	M	9	fibroblasts	not integrative	episomal	control
32	FiPS Ctrl2-Ep6F-8	M	2.5	fibroblasts	not integrative	episomal	control
33	FiPS Ctrl1-mR5F-6	M	9	fibroblasts	not integrative	mRNA	control
34	FiPS Ctrl2-mR5F-6	M	2.5	fibroblasts	not integrative	mRNA	control
35	FiPS Ctrl1-SV4F-7	M	9	fibroblasts	not integrative	Sendai virus	control
36	FiPS Ctrl2-SV4F-1	M	2.5	fibroblasts	not integrative	Sendai virus	control
37	FiPS Ctrl2-R4F-5	M	2.5	fibroblasts	integrative	retrovirus	control
38	FiPS Ctrl1-R4F-4	M	9	fibroblasts	integrative	retrovirus	control
39	UCiPS Ctrl5-R4F-25	F	58	urine cells	integrative	retrovirus	control
44	[MS] FiPS1-R4F-3	F	8	fibroblasts	integrative	retrovirus	multiple sclerosis	TT genotype of the TNFRSF1A polymorphism rs1800693
45	[MS] FiPS2-R4F-10	M	44	fibroblasts	integrative	retrovirus	multiple sclerosis	TT genotype of the TNFRSF1A polymorphism rs1800693
46	[MS] FiPS3-R4F-1	M	41	fibroblasts	integrative	retrovirus	multiple sclerosis	CC genotype of the TNFRSF1A polymorphism rs1800693
47	[MS] FiPS4-R4F-1	F	49	fibroblasts	integrative	retrovirus	multiple sclerosis	CC genotype of the TNFRSF1A polymorphism rs1800693
48	[MS] FiPS5-R4F-6	F	42	fibroblasts	integrative	retrovirus	multiple sclerosis	TT genotype of the TNFRSF1A polymorphism rs1800693
49	[MS] FiPS6-R4F-2	F	49	fibroblasts	integrative	retrovirus	multiple sclerosis	CC genotype of the TNFRSF1A polymorphism rs1800693
50	[DUPSW]FiPS301-R4F-1	F	15	fibroblasts	integrative	retrovirus	Williams-Beuren syndrome	7q.11.23 deletion
51	[DUP7]FiPS4-R4F-2	F	13	fibroblasts	integrative	retrovirus	Autism	7q.11.23 duplication
52	[SWB]FiPS1-R4F-5	F	15	fibroblasts	integrative	retrovirus	Williams-Beuren syndrome	7q.11.23 deletion
53	[SWB]FiPS5-R4F-1	F	15	fibroblasts	integrative	retrovirus	Williams-Beuren syndrome	7q.11.23 deletion
54	[AS] FiPS1-Ep6F-2	F	25	fibroblasts	not integrative	episomal	Alport sindrome	gene COL4A3, c.[345delG]; [345delG], p.[P116Lfs*37], Exon6
55	[AS] FiPS2-Ep6F-28	M	25	fibroblasts	not integrative	episomal	Alport sindrome	gene COL4A5, c3722G>A (G1241D)
56	[AS] FiPS3-Ep6F-9	M	41	fibroblasts	not integrative	episomal	Alport sindrome	gene COL4A5, c4034G>A (G1345D)
57	[IDDM-1] FiPS 1-13 - Ep6F-9	M	38	fibroblasts	not integrative	episomal	Diabetes
58	SWB FiPS 159-R4F-4	M	14	fibroblasts	integrative	retrovirus	Williams-Beuren syndrome	7q11.23 deletion
59	SWB FiPS 344-R4F-2	M	7	fibroblasts	integrative	retrovirus	Williams-Beuren syndrome	7q11.23 deletion
60	DUPSW FiPS 501-R4F-2	M	17	fibroblasts	integrative	retrovirus	Autism	7q11.23 duplication
61	DUPSW FiPS701 R4F-6	M	4	fibroblasts	integrative	retrovirus	Autism	7q11.23 duplication
65	OCD FiPS1-Ep6F-16	F	54	fibroblasts	not integrative	episomal	Obssesive compulsive diorder
66	OCD FiPS2-Ep6F-10	F	51	fibroblasts	not integrative	episomal	Obssesive compulsive diorder
67	BST PBiPS1-Sv4F-1	F	52	Perif. blood monon. cells	not integrative	Sendai virus	rare bood type	fenotype vel negative
68	BST PBiPS2-Sv4F-6	M	62	Perif. blood monon. cells	not integrative	Sendai virus	control rare blood types
69	CT PBiPS1-Sv4F-1	M	7	Perif. blood monon. cells	not integrative	Sendai virus	Cardiotoxicity to anthracyclines
70	CT PBiPS3-Sv4F-3	M	7	Perif. blood monon. cells	not integrative	Sendai virus	Cardiotoxicity to anthracyclines
71	Ctrl BS PBiPS37-Sv4F-1	M	55	Perif. blood monon. cells	not integrative	Sendai virus	control
72	[DUP7] FiPS-4F-3-1	F	8	fibroblasts	integrativo	retrovirus	Autism	7q.11.23 duplication
73	[DUP7] FiPS-4F-6	F	14	fibroblasts	integrativo	retrovirus	Autism	7q.11.23 duplication
74	[SWB] FiPS-4F-5-6	F	15	fibroblasts	integrativo	retrovirus	Williams-Beuren syndrome	7q.11.23 deletion
75	[SWB]FiPS5-R4F-1	F	15	fibroblasts	integrative	retrovirus	Williams-Beuren syndrome	7q.11.23 deletion
76	BS PBiPS46-Sv4F-10	M	65	Perif. blood monon. cells	not integrative	Sendai virus	Brugada syndrome	Seven genetic variants within the SCN10A gene
77	CT PBiPS2-Sv4F-1	M	14	Perif. blood monon. cells	not integrative	Sendai virus	Cardiotoxicity to anthracyclines
78	NW FiPS 10II.3-R4F-H1	F	40	fibroblasts	integrativo	retrovirus	Atypical deletion of the 7q11.23 Williams-Beuren Syndrome region	Atypical deletion of the 7q11.23 Williams-Beuren Syndrome region
79	OCD FiPS3-Ep6F-6	M	44	fibroblasts	not integrative	episomal	Obssesive compulsive disorder
80	THD FiPS A1 Ep6F-17	F	8	fibroblasts	no integrativo	episomal	Tyrosine Hydroxylase Deficiency	TH Gene c.698G>A, p.R233H/c.698G>A, p.R233H
81	THD FiPS B1 Ep6F-15	F	15	fibroblasts	no integrativo	episomal	Tyrosine Hydroxylase Deficiency	TH Gene c.982C>T; R238W/c.1196 C>T, p.T399M
82	CD34 iPS1-Sv4F-B8	M	0	CD34 cord blood cells	not integrative	Sendai virus	control
83	Hz 30-18-3 CBiPS2-Sv4F-D10	M	0	CD34 cord blood cells	not integrative	Sendai virus	control
84	Hz 3-7-15 CBiPS3-Sv4F-E9	M	0	CD34 cord blood cells	not integrative	Sendai virus
85	Hz 24-7-15 CBiPS7-Sv4F-I12	M	0	CD34 cord blood cells	not integrative	Sendai virus	control
86	MD FiPS3304-Sv4F-5	M	14	fibroblasts	not integrative	Sendai virus	mitocondrial disease
87	MD-FiPS3236-Sv4F-9	M	5	fibroblasts	not integrative	Sendai virus	mitocondrial disease
88	Hz-11-27-1-CBiPS8-Sv4F-J1	F	0	CD34 cord blood cells	not integrative	Sendai virus	control
89	PMM2-CDG FiPS48-Sv4F-7	F	1	fibroblasts	not integrative	Sendai virus	PMM2-CDG	IVS7-9T>G/p.T237M in PMM2
90	Hz 3-7-15 CBiPS3-Sv4F-E9	M	0	CD34 cord blood cells	not integrative	Sendai virus	control
91	Hz-1-8-3-CBiPS4-Sv4F-F6	F	0	CD34 cord blood cells	not integrative	Sendai virus	control
92	Hz 33-14-1 CBiPS6-Sv4F-H6	F	0	CD34 cord blood cells	not integrative	Sendai virus	control

Available hESC lines

Name	Karyotype	Comments
Name	Karyotype	Comments
ES[2]	46,XY
ES[3]	46,XY
ES[4]	46,XY
ES[5]	46,XY
ES[6]	46,XY
ES[7]	46,XY
ES[8]	46,XY
ES[9]	46,XY
ES[10]	46, XX
ES[11-EM]	46, XY	c.484delC in the exon 2 of the gen EXT2 responsible of the multiple exostosis type 2
pES[12]	46, XX	hESc line derivated from a parthenogenetic embryo
bES[13]	46, XX	hESC line derivated from a single blastomere

Our current QC process include tests for:

Purity- Mycoplasma contamination
Identity- Short Tandem Repeats (STR)
Stability- Karyotyping
Stemness: absence of reprogramming factors, pluripotent gene expression, and differentiation capacity

How to request hPSC lines

Requests for cell lines must first be authorized by an Ethics Committee and Comisión de Garantías para la Donación y Utilización de Células y Tejidos Humanos del Instituto de Salud Carlos III.

Request of Generation of iPSC I:

Request of Generation of iPSC II (Donors):