Available hiPSC lines
nº | Name | Gender | Age | Cell Type | Reprogram. Method | Type | Disease | Mutation |
---|---|---|---|---|---|---|---|---|
nº | Name | Gender | Age | Cell Type | Reprogram. Method | Type | Disease | Mutation |
1 | KiPS3F-7 | M | ? | keratinocytes | integrative | retrovirus | control | |
2 | KiPS4F-1 | M | ? | keratinocytes | integrative | retrovirus | control | |
3 | KiPS4F-8 | M | ? | keratinocytes | integrative | retrovirus | control | |
4 | cFA404-KiPS4F-1 | M | ? | keratinocytes | integrative | retrovirus | corrected Fanconi anemia | |
5 | cFA404-KiPS4F-3 | M | ? | keratinocytes | integrative | retrovirus | corrected Fanconi anemia | |
6 | XF-iPSF44-3F-1 | M | 3 | fibroblasts | integrative | retrovirus | control | |
7 | XF-iPSF44-3F-2 | M | 3 | fibroblasts | integrative | retrovirus | control | |
8 | [GA]FiPS4F | F | ? | fibroblasts | integrative | retrovirus | Glutaril aciduria dehidrog. defic. | |
9 | HKiPS4F | F | 30 | hair keratinocytes | integrative | retrovirus | control | |
10 | CBiPS6-2F-4 | M | 0 | CD133+ cord blood | integrative | retrovirus | control | |
11 | CBiPS30-4F-3 | M | 0 | CD133+ cord blood | integrative | retrovirus | control | |
12 | CBiPS30-4F-5 | M | 0 | CD133+ cord blood | integrative | retrovirus | control | |
13 | CBiPS32-2F-2 | F | 0 | CD133+ cord blood | integrative | retrovirus | control | |
14 | FiPS-3F-1 | M | 3 | fibroblasts | integrative | retrovirus | control | |
15 | CBiPS32-3F-10 | F | 0 | CD133+ cord blood | integrative | retrovirus | control | |
16 | CBiPS32-3F-12 | F | 0 | CD133+ cord blood | integrative | retrovirus | control | |
17 | [CRTRd]FiPS3067-4F-9 | M | adult | fibroblasts | integrative | retrovirus | Creatine Deficiency Syndrome | gene CRTR, c.1631 C>T |
18 | [CRTRd]FiPS3819-4F-2 | M | adult | fibroblasts | integrative | retrovirus | Creatine Deficiency Syndrome | gene CRTR, c.1396 G>A |
19 | [AD]FiPSAG07645-4F-17 | F | adult | fibroblasts | integrative | retrovirus | Alzheimer disease | gene PSEN1, A246E |
20 | [PD] FiPS022-V4F-15 | M | ? | fibroblasts | integrative | retrovirus | Parkinson disease | gene LRKK2 G2019S heterozygote with early onset PD (40) |
21 | [GD]FiPS-4F-21c | F | ? | fibroblasts | integrative | lentivirus | Gaucher disease | gene GBA1, 721 G→A, 1448 T→C |
22 | [TSD] FiPS-4F-3-1 | M | ? | fibroblasts | integrative | retrovirus | Tay-Sachs disease | gene HEXA, heterozygote mutation c.1260G> C, c.1330 +1 G> A |
23 | FiPS-4F-7 | M | 3 | fibroblasts | integrative | retrovirus | control | |
24 | FiPS-4F-8 | M | 3 | fibroblasts | integrative | retrovirus | control | |
25 | [ctrl.PD]FiPS005-4F-9 | F | 56 | fibroblasts | integrative | retrovirus | control (sister Parkinson disease) | control of [PD]FiPS006-4F-11 |
26 | [PD]FiPS031-4F-1 | M | 48 | fibroblasts | integrative | retrovirus | Parkinson disease | gene SNCA, A53T |
27 | [PD]FiPS006-4F-11 | F | 53 | fibroblasts | integrative | retrovirus | Parkinson disease | gene PINK1, Q456Xhom |
28 | CBiPS 2F-1c | F | 0 | CD133+ cord blood | integrative | retrovirus | control | |
29 | CBiPS 4F-10 | F | 0 | CD133+ cord blood | integrative | retrovirus | control | |
30 | CBiPS 4F-3a | F | 0 | CD133+ cord blood | integrative | retrovirus | control | |
31 | FiPS Ctrl1-Ep6F-5 | M | 9 | fibroblasts | not integrative | episomal | control | |
32 | FiPS Ctrl2-Ep6F-8 | M | 2.5 | fibroblasts | not integrative | episomal | control | |
33 | FiPS Ctrl1-mR5F-6 | M | 9 | fibroblasts | not integrative | mRNA | control | |
34 | FiPS Ctrl2-mR5F-6 | M | 2.5 | fibroblasts | not integrative | mRNA | control | |
35 | FiPS Ctrl1-SV4F-7 | M | 9 | fibroblasts | not integrative | Sendai virus | control | |
36 | FiPS Ctrl2-SV4F-1 | M | 2.5 | fibroblasts | not integrative | Sendai virus | control | |
37 | FiPS Ctrl2-R4F-5 | M | 2.5 | fibroblasts | integrative | retrovirus | control | |
38 | FiPS Ctrl1-R4F-4 | M | 9 | fibroblasts | integrative | retrovirus | control | |
39 | UCiPS Ctrl5-R4F-25 | F | 58 | urine cells | integrative | retrovirus | control | |
44 | [MS] FiPS1-R4F-3 | F | 8 | fibroblasts | integrative | retrovirus | multiple sclerosis | TT genotype of the TNFRSF1A polymorphism rs1800693 |
45 | [MS] FiPS2-R4F-10 | M | 44 | fibroblasts | integrative | retrovirus | multiple sclerosis | TT genotype of the TNFRSF1A polymorphism rs1800693 |
46 | [MS] FiPS3-R4F-1 | M | 41 | fibroblasts | integrative | retrovirus | multiple sclerosis | CC genotype of the TNFRSF1A polymorphism rs1800693 |
47 | [MS] FiPS4-R4F-1 | F | 49 | fibroblasts | integrative | retrovirus | multiple sclerosis | CC genotype of the TNFRSF1A polymorphism rs1800693 |
48 | [MS] FiPS5-R4F-6 | F | 42 | fibroblasts | integrative | retrovirus | multiple sclerosis | TT genotype of the TNFRSF1A polymorphism rs1800693 |
49 | [MS] FiPS6-R4F-2 | F | 49 | fibroblasts | integrative | retrovirus | multiple sclerosis | CC genotype of the TNFRSF1A polymorphism rs1800693 |
50 | [DUPSW]FiPS301-R4F-1 | F | 15 | fibroblasts | integrative | retrovirus | Williams-Beuren syndrome | 7q.11.23 deletion |
51 | [DUP7]FiPS4-R4F-2 | F | 13 | fibroblasts | integrative | retrovirus | Autism | 7q.11.23 duplication |
52 | [SWB]FiPS1-R4F-5 | F | 15 | fibroblasts | integrative | retrovirus | Williams-Beuren syndrome | 7q.11.23 deletion |
53 | [SWB]FiPS5-R4F-1 | F | 15 | fibroblasts | integrative | retrovirus | Williams-Beuren syndrome | 7q.11.23 deletion |
54 | [AS] FiPS1-Ep6F-2 | F | 25 | fibroblasts | not integrative | episomal | Alport sindrome | gene COL4A3, c.[345delG]; [345delG], p.[P116Lfs*37], Exon6 |
55 | [AS] FiPS2-Ep6F-28 | M | 25 | fibroblasts | not integrative | episomal | Alport sindrome | gene COL4A5, c3722G>A (G1241D) |
56 | [AS] FiPS3-Ep6F-9 | M | 41 | fibroblasts | not integrative | episomal | Alport sindrome | gene COL4A5, c4034G>A (G1345D) |
57 | [IDDM-1] FiPS 1-13 - Ep6F-9 | M | 38 | fibroblasts | not integrative | episomal | Diabetes | |
58 | SWB FiPS 159-R4F-4 | M | 14 | fibroblasts | integrative | retrovirus | Williams-Beuren syndrome | 7q11.23 deletion |
59 | SWB FiPS 344-R4F-2 | M | 7 | fibroblasts | integrative | retrovirus | Williams-Beuren syndrome | 7q11.23 deletion |
60 | DUPSW FiPS 501-R4F-2 | M | 17 | fibroblasts | integrative | retrovirus | Autism | 7q11.23 duplication |
61 | DUPSW FiPS701 R4F-6 | M | 4 | fibroblasts | integrative | retrovirus | Autism | 7q11.23 duplication |
65 | OCD FiPS1-Ep6F-16 | F | 54 | fibroblasts | not integrative | episomal | Obssesive compulsive diorder | |
66 | OCD FiPS2-Ep6F-10 | F | 51 | fibroblasts | not integrative | episomal | Obssesive compulsive diorder | |
67 | BST PBiPS1-Sv4F-1 | F | 52 | Perif. blood monon. cells | not integrative | Sendai virus | rare bood type | fenotype vel negative |
68 | BST PBiPS2-Sv4F-6 | M | 62 | Perif. blood monon. cells | not integrative | Sendai virus | control rare blood types | |
69 | CT PBiPS1-Sv4F-1 | M | 7 | Perif. blood monon. cells | not integrative | Sendai virus | Cardiotoxicity to anthracyclines | |
70 | CT PBiPS3-Sv4F-3 | M | 7 | Perif. blood monon. cells | not integrative | Sendai virus | Cardiotoxicity to anthracyclines | |
71 | Ctrl BS PBiPS37-Sv4F-1 | M | 55 | Perif. blood monon. cells | not integrative | Sendai virus | control | |
72 | [DUP7] FiPS-4F-3-1 | F | 8 | fibroblasts | integrativo | retrovirus | Autism | 7q.11.23 duplication |
73 | [DUP7] FiPS-4F-6 | F | 14 | fibroblasts | integrativo | retrovirus | Autism | 7q.11.23 duplication |
74 | [SWB] FiPS-4F-5-6 | F | 15 | fibroblasts | integrativo | retrovirus | Williams-Beuren syndrome | 7q.11.23 deletion |
75 | [SWB]FiPS5-R4F-1 | F | 15 | fibroblasts | integrative | retrovirus | Williams-Beuren syndrome | 7q.11.23 deletion |
76 | BS PBiPS46-Sv4F-10 | M | 65 | Perif. blood monon. cells | not integrative | Sendai virus | Brugada syndrome | Seven genetic variants within the SCN10A gene |
77 | CT PBiPS2-Sv4F-1 | M | 14 | Perif. blood monon. cells | not integrative | Sendai virus | Cardiotoxicity to anthracyclines | |
78 | NW FiPS 10II.3-R4F-H1 | F | 40 | fibroblasts | integrativo | retrovirus | Atypical deletion of the 7q11.23 Williams-Beuren Syndrome region | Atypical deletion of the 7q11.23 Williams-Beuren Syndrome region |
79 | OCD FiPS3-Ep6F-6 | M | 44 | fibroblasts | not integrative | episomal | Obssesive compulsive disorder | |
80 | THD FiPS A1 Ep6F-17 | F | 8 | fibroblasts | no integrativo | episomal | Tyrosine Hydroxylase Deficiency | TH Gene c.698G>A, p.R233H/c.698G>A, p.R233H |
81 | THD FiPS B1 Ep6F-15 | F | 15 | fibroblasts | no integrativo | episomal | Tyrosine Hydroxylase Deficiency | TH Gene c.982C>T; R238W/c.1196 C>T, p.T399M |
82 | CD34 iPS1-Sv4F-B8 | M | 0 | CD34 cord blood cells | not integrative | Sendai virus | control | |
83 | Hz 30-18-3 CBiPS2-Sv4F-D10 | M | 0 | CD34 cord blood cells | not integrative | Sendai virus | control | |
84 | Hz 3-7-15 CBiPS3-Sv4F-E9 | M | 0 | CD34 cord blood cells | not integrative | Sendai virus | ||
85 | Hz 24-7-15 CBiPS7-Sv4F-I12 | M | 0 | CD34 cord blood cells | not integrative | Sendai virus | control | |
86 | MD FiPS3304-Sv4F-5 | M | 14 | fibroblasts | not integrative | Sendai virus | mitocondrial disease | |
87 | MD-FiPS3236-Sv4F-9 | M | 5 | fibroblasts | not integrative | Sendai virus | mitocondrial disease | |
88 | Hz-11-27-1-CBiPS8-Sv4F-J1 | F | 0 | CD34 cord blood cells | not integrative | Sendai virus | control | |
89 | PMM2-CDG FiPS48-Sv4F-7 | F | 1 | fibroblasts | not integrative | Sendai virus | PMM2-CDG | IVS7-9T>G/p.T237M in PMM2 |
90 | Hz 3-7-15 CBiPS3-Sv4F-E9 | M | 0 | CD34 cord blood cells | not integrative | Sendai virus | control | |
91 | Hz-1-8-3-CBiPS4-Sv4F-F6 | F | 0 | CD34 cord blood cells | not integrative | Sendai virus | control | |
92 | Hz 33-14-1 CBiPS6-Sv4F-H6 | F | 0 | CD34 cord blood cells | not integrative | Sendai virus | control |
Available hESC lines
Name | Karyotype | Comments |
---|---|---|
Name | Karyotype | Comments |
ES[2] | 46,XY | |
ES[3] | 46,XY | |
ES[4] | 46,XY | |
ES[5] | 46,XY | |
ES[6] | 46,XY | |
ES[7] | 46,XY | |
ES[8] | 46,XY | |
ES[9] | 46,XY | |
ES[10] | 46, XX | |
ES[11-EM] | 46, XY | c.484delC in the exon 2 of the gen EXT2 responsible of the multiple exostosis type 2 |
pES[12] | 46, XX | hESc line derivated from a parthenogenetic embryo |
bES[13] | 46, XX | hESC line derivated from a single blastomere |
Our current QC process include tests for:
- Purity- Mycoplasma contamination
- Identity- Short Tandem Repeats (STR)
- Stability- Karyotyping
- Stemness: absence of reprogramming factors, pluripotent gene expression, and differentiation capacity
How to request hPSC lines
Requests for cell lines must first be authorized by an Ethics Committee and Comisión de Garantías para la Donación y Utilización de Células y Tejidos Humanos del Instituto de Salud Carlos III.
Request of Generation of iPSC I:
Request of Generation of iPSC II (Donors):