A Heart-on-a-Chip to better understand how the human heart responds to drugs

Researchers from IDIBELL and IMB-CNM have developed a new vascularized cardiac model: a chip integrated into living heart tissue generated from human stem cells, which could advance our understanding of cardiotoxicity, one of the main barriers currently facing drug development.
The new model is emerging as an alternative to reduce the use of animal models and avoid the rejection of promising drugs due to an overestimation of their cardiac toxicity.

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